NG-Test® CARBA 5 is a rapid, qualitative immunochromatographic assay designed for the detection and differentiation of the five most clinically significant carbapenemase enzymes directly from carbapenem non-susceptible bacterial colonies. By detecting enzyme expression rather than genetic material, it provides clinically relevant results that support timely therapeutic and infection control decisions.Key Features
- Detects KPC, OXA-48-like, NDM, VIM, and IMP carbapenemases
- Results in 15 minutes with approximately 1 minute of hands-on time
- 100% sensitivity and 99.9% specificity (published data, PMC8246204)
- FDA 510(k) cleared — the only FDA-cleared multiplex phenotypic carbapenemase test
- Compliant with 2025 CLSI M100 recommendations
- Compatible with colonies grown on:
- HardyCHROM™ CRE
- Blood Agar
- MacConkey Agar
- No specialized instrumentation or analyzer required
- More cost-effective than many molecular (PCR) methods
- Detects active carbapenemase expression, providing clinically actionable information for treatment decisions
Intended Use
NG-Test® CARBA 5 is intended for use in:
- Clinical microbiology laboratories
- Hospital infection prevention and infection control programs
- Antimicrobial stewardship teams
- Public health laboratories
- Academic and university research laboratories
